L\u2019Agence nationale de s\u00e9curit\u00e9 du m\u00e9dicament et des produits de sant\u00e9 (ANSM) signale, le 25 ao\u00fbt 2026, un nouveau cas d\u2019erreur m\u00e9dicamenteuse grave li\u00e9 \u00e0 une confusion entre les deux dosages du m\u00e9dicament Siklos (hydroxycarbamide), 100 mg et 1 000 mg, lors de la d\u00e9livrance en officine. L\u2019agence appelle les pharmaciens \u00e0 une vigilance accrue au moment de la dispensation.<\/p>\n
Siklos est indiqu\u00e9 chez les adultes et les enfants de plus de 2 ans atteints de dr\u00e9panocytose pour pr\u00e9venir les crises vaso-occlusives douloureuses r\u00e9currentes, y compris celles du syndrome thoracique aigu. Deux dosages sont commercialis\u00e9s (100 mg et 1 000 mg), dont les conditionnements se distinguent par des couleurs diff\u00e9rentes et un aspect sp\u00e9cifique, pr\u00e9cis\u00e9ment pour limiter les risques de confusion. L\u2019ANSM souligne que ces erreurs peuvent entra\u00eener des situations de surdosage ou de sous-dosage, avec des cons\u00e9quences potentiellement graves pour les patients.<\/p>\n
L\u2019agence rappelle l\u2019existence de documents de r\u00e9duction des risques, notamment une fiche remise par le prescripteur au patient en m\u00eame temps que l\u2019ordonnance, destin\u00e9e \u00e0 \u00eatre transmise au pharmacien pour s\u00e9curiser la d\u00e9livrance. Ce nouvel \u00e9v\u00e8nement renforce l\u2019alerte sur le risque de confusion en ville et justifie le maintien et le renforcement des mesures de sensibilisation des professionnels de sant\u00e9 \u00e0 la s\u00e9curisation du circuit du m\u00e9dicament.\u00a0(contenu r\u00e9sum\u00e9 par l’IA)Lire la Suite<\/a>\u200b<\/p>","protected":false},"excerpt":{"rendered":" L\u2019Agence nationale de s\u00e9curit\u00e9 du m\u00e9dicament et des produits de sant\u00e9 (ANSM) signale, le 25 ao\u00fbt 2026, un nouveau cas d\u2019erreur m\u00e9dicamenteuse grave li\u00e9 \u00e0 une confusion entre les deux 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